Therapeutische Umschau. Revue thérapeutique
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Acute ischaemic stroke - Update Abstract. Intravenous thrombolysis and / or endovascular therapy are effective and safe in acute ischaemic stroke if patients are selected accordingly. Despite bleeding complications, disability rates may be lowered by treatment. Latest studies investigated intravenous thrombolysis with rt-PA in a treatment window of > 4.5 hours after symptom onset or in case of unknown symptom onset, the application of tenecteplase as thrombolytic agent applied intravenously with and without endovascular therapy, endovascular therapy in a treatment window of > 6 - 24 hours or in case of unknown symptom onset as well as outcome in dependence of general anaesthesia or conscious sedation for endovascular therapy.