Biological psychiatry
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Biological psychiatry · Sep 2005
Comparative Study Clinical TrialEffects of 12 months of vagus nerve stimulation in treatment-resistant depression: a naturalistic study.
The need for effective, long-term treatment for recurrent or chronic, treatment-resistant depression is well established. ⋯ These 1-year open trial data found VNS to be well tolerated, suggesting a potential long-term, growing benefit in treatment-resistant depression, albeit in the context of changes in depression treatments. Comparative long-term data are needed to determine whether these benefits can be attributed to VNS.