Revista médica de Chile
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Revista médica de Chile · Nov 2014
[Correlation between aPTT and antifactor Xa to determine therapeutic ranges for unfractionated heparin].
The therapeutic range (TR) of activated partial thromboplastin time (aPTT) for unfractionated heparin (UFH) dosing was established in the 1970 decade. Since then aPTT determination has changed. Current TR may be sub or supra-therapeutic depending on the reagents of the test, and therefore, responsible for complications of therapy. ⋯ According to current recommendations, validation of aPTT determination with reference techniques should be done in every institution.