Revista médica de Chile
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Taxanes are a class of chemotherapeutic agents with common associated dermatologic adverse events, such as skin hyperpigmentation, hand-foot skin syndrome, paronychia and onycholysis. Taxane-induced scleroderma is rare. Few cases with skin findings resembling systemic sclerosis, have been reported after the administration of these agents. We report two cases with stage IV breast cancer, aged 66 and 71 years, who developed sclerodermic skin lesions in their extremities after starting treatment with placlitaxel and nabplaclitaxel respectively.
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Revista médica de Chile · May 2021
Consequences of COVID-19 pandemic on myocardial infarction reperfusion therapy and prognosis.
Background The coronavirus disease (COVID-19) pandemic affected the prompt diagnosis and treatment of Acute myocardial infarction (AMI).
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Monoclonal gammopathies of uncertain significance (MGUS) correspond to pre-malignant hematological disorders characterized by the production of a monoclonal protein and infiltration of less than 10% of the bone marrow by plasma cells. Its importance lies in the risk of progression to malignant disorders and in the association with different renal, neurological and skin manifestations. ⋯ In this context, the role of the dermatologist is crucial in the suspicion of different haematological disorders based on skin manifestations and in the multidisciplinary treatment of these patients. In this article, we carry out an exhaustive review of the literature published in this area and propose a screening algorithm for MGs in patients with specific skin diseases.
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Revista médica de Chile · May 2021
[Portrayal of cancer prevalence and mortality in Chilean digital media].
Cancer is the second death cause in Chile. The Chilean National Cancer Act will secure treatment and labor protection for people diagnosed with cancer. ⋯ Our results are consistent with international studies. We should expect the delivery of complete, timely and effective information about cancer in communication media, aiming to educate the population and reinforce prevention.