Revista médica de Chile
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Revista médica de Chile · Nov 2021
[Clinical and epidemiological characteristics of the Philadelphia negative myeloproliferative neoplasms in Chile].
Philadelphia-negative myeloproliferative neoplasms (Ph-MPN) are chronic hematological disorders characterized by the overproduction of one or more mature myeloid blood cell lineages. Classical Ph-MPN are polycythemia vera (PV), essential thrombocytopenia (ET) and primary myelofibrosis (PMF). ⋯ ET is the most frequent Ph-MPN. The mean incidence was lower than reported in the literature, in part because of a sub diagnosis.
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Revista médica de Chile · Nov 2021
[The possible poisons contained in the arrow that killed Ferdinand Magellan].
Ferdinand Magellan's maritime expedition that resulted in the circumnavigation of the Earth and the discovery of the strait that bears his name is among the greatest feats in history. The trip, which took more than three years, was not completed by Magellan, who died on the island of Mactan, Philippines in a scuffle with the locals. As reported in Magellan's voyage journal written by Pigafetta, Magellan died after receiving a poisoned arrow in his right leg. ⋯ These poisons are mainly derived from Aconitum and other species, such as Strychnos, Lophopetalum, Beaumontia, and Strophanthus. They contain cardiac alkaloids and glycosides, which can produce neurological and cardiac effects in just a few minutes. We argue that these toxic effects hindered the withdrawal of Magellan from the beach, facilitating his death in hands of the locals.
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Excess all-cause mortality is an epidemiologic tool to assess the impact of pandemics or other events on the population. ⋯ The oldest age groups were the most vulnerable in terms of mortality during the COVID-19 pandemic in Chile.
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Revista médica de Chile · Nov 2021
Review[The effects of COVID-19 pandemic on the prevention, diagnosis and treatment of oncologic diseases].
The COVID-19 pandemic had a significant impact on the management of chronic diseases such as cancer. Comprehensive care, from preventive strategies to palliative care for cancer patients, has been strongly affected by multiple factors associated with the pandemic. The hampering of early detection, timely diagnosis, as well as recommended treatment and follow-up are side effects of SARS-CoV-2 infection worldwide that will undoubtedly produce changes in the prognosis and survival of oncologic patients. Through this narrative review, we report global and local figures of these effects, as a first approach to tackle the challenge of updating cancer care.