Revista médica de Chile
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Revista médica de Chile · Aug 2021
[Telemedicine: expected challenges in Chile based on the experience in the United States during the pandemic].
Telemedicine has had a significant role during the outbreak of COVID-19. The experience in the United States has shown advantages and some challenges that need to be addressed to include telemedicine as an established part of the health system. ⋯ In this study, we classify the barriers and difficulties for telemedicine into three areas: accessibility, cyber security, and medical liability. We argue that Chile will have to deal with similar obstacles to include telemedicine as a regular health service for the entire population.
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Revista médica de Chile · Aug 2021
[Coronary artery bypass grafting or percutaneous coronary intervention in patients with severe three vessel disease].
Recent randomized controlled trials confirmed the beneficial outcomes with coronary artery bypass grafting (CABG) compared with percutaneous coronary intervention (PCI) in patients with severe three-vessel coronary artery and left main disease. An increased long-term survival after CABG is associated with a reduction in spontaneous myocardial infarction and repeat revascularization rates. While PCI treats only flow-limiting lesions, CABG treats the whole coronary artery, preventing events in the future. Due to different clinical and anatomic factors affecting the outcomes, the heart team should formulate treatment assignment recommendations.
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Revista médica de Chile · Aug 2021
Case ReportsPrimary myocardial diffuse large B cell lymphoma. Report of one case.
Primary myocardial involvement of Diffuse Large B-Cell lymphoma is extremely rare, accounting for 0.5 % of all lymphomas. We report a 65-year-old male, presenting with an acute cardiac tamponade, which was drained. ⋯ He received 6 cycles of rituximab, cyclophosphamide, vincristine, and prednisone (R-CVP), without response. Finally, a palliative chemotherapy with gemcitabine plus oxaliplatin was prescribed.
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Revista médica de Chile · Jul 2021
Review[Pharmacokinetic interactions of fruit juices and herbal preparations].
Drug disposition in the human body is strongly influenced by transporters and metabolizing enzymes expressed in key organs including intestine, liver and kidney. Since drugs and chemicals present in foods such as fruit juices and herb-based products are substrates of the above-mentioned proteins, there is a high probability of pharmacokinetic interactions. Findings from preclinical and clinical studies helped to characterize the mechanisms by which the components of fruit juices and herbs act as perpetrators of pharmacokinetic interactions. The aim of this review is to provide an overview of pharmacokinetic fruit juice- and herb-drug interactions that could be relevant in the clinical setting.