Revista médica de Chile
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Revista médica de Chile · Dec 2023
Case ReportsGastroparesis associated to isoniazid. First description.
Isoniazid, a central compound in the treatment of active or latent tuberculosis, is associated with various adverse reactions, including hepatitis and polyneuropathy. The latter is due to functional pyridoxine depletion and can be avoided by appropriate doses and supplementation with pyridoxine. We present the case of a patient with several previous treatment abandonments for active pulmonary tuberculosis who evolved with late postprandial vomiting due to gastroparesis documented by nuclear medicine gastric emptying tests after a new treatment onset. ⋯ The association of gastroparesis with isoniazid was considered definitive when applying at least two causality protocols. Gastroparesis associated with isoniazid should be added to the list of adverse effects associated with this drug, even in patients receiving pyridoxine supplementation. Its recognition is initially clinical, can be confirmed with nuclear medicine studies, and affects the eradication of Mycobacterium tuberculosis.
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Revista médica de Chile · Dec 2023
Case ReportsSuccessful use of daptomycin and cefazolin in a case of persistent bacteremia caused by community acquired-methicillin resistant Staphylococcus aureus in a pregnant woman. Case report.
We present the case of a pregnant woman with community-acquired methicillin-resistant Staphylococcus aureus bacteremia who required combined treatment with daptomycin and cefazolin for control after failure of an initial treatment with vancomycin. She had a favorable evolution, and the study of family contacts revealed a phenotypic and genetically similar isolate in a nasal sample from his mother. ⋯ This case reveals that bacteremia caused by methicillin-resistant Staphylococcus aureus can affect pregnant women, and that the use of combined therapies may be necessary for its control. Sometimes, family contacts can carry this agent, and an eradication treatment is suggested..
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Revista médica de Chile · Dec 2023
Case ReportsIntestinal perforation as a form of presentation of a small bowel calcifying fibrous tumor.
Calcifying fibrous tumor (CFT) is a rare, benign, mesenchymal tumor. It has a slight female predominance, and it can appear in any range of age. It can be in the extremities, neck, and gastrointestinal tract, but it has also been described in other locations. ⋯ Histopathological study described the presence of a calcifying fibrous tumor. Spindle cells were positive for CD34, Factor XIIIa and vimentin. To our knowledge, this is the first case of intestinal perforation secondary to a calcifying fibrous tumor described in the literature.
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Revista médica de Chile · Dec 2023
[Cultural Adaptation and Validation of the Self-Efficacy Instrument for Chronic Disease Management in the Chilean Population].
To adapt and validate the Latin-Spanish version of the Self-Efficacy to Manage Chronic Disease (SEMCD-S) for the Chilean population. ⋯ The SEMCD-S-Ch is understandable, reliable, and useful for a brief and competent assessment of self-efficacy in people with chronic diseases under control in primary health care.
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Revista médica de Chile · Dec 2023
Case Reports[Solitary pulmonary nodule as an unusual presentation of infection by Mycobacterium abscessus. Report of a clinical case].
Nontuberculous mycobacteria are a ubiquitous species of bacteria that can produce chronic pulmonary infectious disease in humans. The clinical manifestations are diverse, from an indolent solitary pulmonary nodule up to fibrocavitary disease which carries a poor prognosis. The presentation as a solitary pulmonary nodule has been described in slowly growing mycobacteria, mainly Mycobacterium avium complex and Mycobacterium kansasii. In the following clinical case, we report an infection by a nontuberculous mycobacteria presenting as a solitary pulmonary nodule caused by Mycobacterium abscessus and its outcomes after surgical resection.