The Nigerian postgraduate medical journal
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Niger Postgrad Med J · Mar 2014
Randomized Controlled Trial Comparative StudyA comparative study between caudal bupivacaine and bupivacaine co-administered with neostigmine for postoperative analgesia in children.
The aim of this study was to compare the duration of postoperative analgesia and possible adverse effects produced by caudal bupivacaine 0.25% at 1 ml/kg with or without 1.5 ug/kg of neostigmine in children undergoing unilateral herniotomy. ⋯ The study shows that the addition of low dose neostigmine to caudal isobaric bupivacaine significantly prolonged the time to first analgesic request and hence significantly reduced postoperative analgesic requirement.