Zhonghua fu chan ke za zhi
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Zhonghua Fu Chan Ke Za Zhi · Feb 2006
[Study of bcl-2 antisense oligodeoxynucleotides on reversal of cisplatin resistance in ovarian cancer cell line A2780/DDP].
To evaluate the influence of bcl-2 antisense oligodeoxynucleotides (AODN) on reversing cisplatin (DDP) resistance in ovarian carcinoma cell lines. ⋯ Through inhibiting the expression of bcl-2 mRNA and protein and increasing the apoptosis, AODN can reverse the resistance to cisplatin in ovarian cancer cell line A2780/DDP.
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Zhonghua Fu Chan Ke Za Zhi · Feb 2006
[Perinatal management and pregnancy outcome in pregnant women with pulmonary hypertension complicating cardiac disease].
To evaluate the pregnancy outcome of women with pulmonary hypertension complicating cardiac disease. ⋯ The rate of heart failure increases gradually with the severity of pulmonary hypertension. The severity of pulmonary hypertension in rheumatic heart disease is higher than in congenital heart disease. The rate of maternal mortality and fetal loss increases in pregnant women with pulmonary hypertension complicating cardiac disease. Perinatal morbidity is higher than normal. Cesarean section is more suitable for those women.