Zhonghua fu chan ke za zhi
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Zhonghua Fu Chan Ke Za Zhi · May 2012
[Re-evaluation of interval debulking surgery in advanced epithelial ovarian cancer].
Previous study showed that interval debulking surgery (IDS) may improve the survival of patients with advanced epithelial ovarian cancer (EOC). The precise significance of IDS needs to be evaluated. ⋯ For advanced EOC patients, IDS has little effect on improving survival. While it is safe and acceptable, also may prolong PFS in those patients who got no visible residual after IDS. The results suggest that IDS might be used as an alternative treatment for advanced EOC patients who cannot obtain optimal PDS in certain local hospitals.
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Zhonghua Fu Chan Ke Za Zhi · May 2012
[Association of the tumor necrosis factor-alpha -1031T/C and its combination with interleukin-6 -634C/G gene polymorphisms with susceptibility to endometriosis].
To investigate the association of tumor necrosis factor-alpha (TNF-α) gene promoter region -1031T/C and its combination with interleukin-6 (IL-6) gene promoter region -634C/G single nucleotide polymorphisms (SNP) with the genetic susceptibility to endometriosis. ⋯ The study demonstrates that there are no significant association between the SNP of TNF-α -1031T/C and genetic susceptibility to endometriosis. However the results indicate that there are significant association between genetic susceptibility to endometriosis and the combination polymorphisms of TNF-α -1031T/C and IL-6 -634C/G.
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Zhonghua Fu Chan Ke Za Zhi · May 2012
[Association between severe preeclampsia and single nucleotide polymorphism of macrophage migration inhibitory factors -173G/C].
To investigate whether single nucleotide polymorphism (SNP) of macrophage migration inhibitory factor (MIF) gene -173G/C is associated with severe preeclampsia. ⋯ The present study suggests that the MIF -173G/C SNP is associated with insulin resistance in severe preeclampsia patients. The CG and CC genotypes increase the degree of insulin resistance, but it is may not associate with susceptibility among severe preeclampsia patients of Han Chinese women.