South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde
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Case Reports
Accidental severe hypercapnia during anaesthesia. Case reports and a review of some physiological effects.
Hypercapnia developed during anaesthesia in 2 patients owing to a nitrous oxide cylinder being filled with carbon dioxide. The aetiology and effects of gross hypercapnia during anaesthesia are reviewed.
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Randomized Controlled Trial Clinical Trial
Flunisolide nasal spray in the treatment of perennial rhinitis.
Twenty patients with perennial rhinitis took part in a double-blind, randomized, cross-over comparison of flunisolide nasal spray (Syntaris; Syntex) and its vehicle. The sprays were used twice daily for 4 weeks and a total daily dose of 200 micrograms flunisolide was used. ⋯ Patient and doctor treatment preferences were significantly in favour of the active spray. Side-effects were mainly confined to nasal irritation and occurred equally in both treatment groups.