Southern medical journal
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Nitric oxide (NO) has recently been found to be the endothelium-derived factor that produces profound relaxation of the vascular smooth muscle. This discovery has led to the experimental use of inhaled NO as a selective pulmonary vasodilator without concomitant systemic vasodilation. ⋯ The therapeutic role, if any, of inhaled NO in other diseases featuring pulmonary hypertension remains unknown. Further research is needed to determine potential toxic effects of NO, development of delivery systems, and monitoring techniques applicable to routine clinical care.
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Gunshot injuries to the head and neck are frequently seen in patients brought to a level I trauma center. These injuries result in great morbidity and mortality and a significant expenditure of health care dollars. Missile injuries to the temporal bone, though less common, can likewise be devastating. ⋯ A series of missile injuries to the temporal bone treated at Tampa General Hospital during 1993 prompted a review of head and neck missile injuries in our trauma registry over the past 4 years (1989 to 1993). More than 100 patients were shot in the head or neck; 25 of them had injury to the temporal bone. Outcomes included facial nerve injury (8), deafness (9), vertigo (3), and death (13).
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As the American health care system struggles to provide universal access to quality care at an acceptable price, many planners focus on rationing as the only way to make available the necessary resources. I discuss some of the ethical, economic, and political issues that relate to health care rationing. ⋯ Because of the absence of an efficient market economy in health care and the certainty of resource constraints, rationing is inevitable in American health care. The primary issues are whether rationing will be done implicitly or explicitly and whether it will be based primarily on ability to pay (as in the present system) or on comparative judgments about the costs and benefits of medical interventions.