Indian journal of ophthalmology
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Indian J Ophthalmol · Jun 1996
Randomized Controlled Trial Clinical TrialA comparative evaluation of pilocarpine 1% and clonidine 0.125% versus timolol 0.5%.
All the presently available antiglaucoma medications have either local or systemic adverse effects. Combinations of drugs are being used not only to increase the effectivity and compliance but also to decrease the incidence and magnitude of side effects. ⋯ Over a period of twelve hours the effectivity of the combination of pilocarpine 1% and clonidine 0.125% was significantly more than that of either drug alone and was found to be similar to that of timolol 0.5%. No local or systemic adverse effects were seen.