Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences
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Beijing Da Xue Xue Bao · Aug 2015
[Detection of cytochrome P450 3A4 gene polymorphism guides for labor analgesia with sufentanil medication].
To investigate the relationship between single nucleotide polymorphisms (SNPs) of cytochrome P450 (CYP450) 3A4 rs2242480 and inter-individual differences of sufentanil consumption in accouchement sans douleur. ⋯ The parturient women carrying CT heterozygotes and TT homozygotes of CYP3A4 rs2242480 required less sufentanil in accouchement sans douleur.
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Beijing Da Xue Xue Bao · Aug 2015
Randomized Controlled Trial[Influence of dexamethasone on the incidence of postoperative nausea and vomiting in breast cancer patients with neoadjuvant chemotherapy].
To evaluate the influence of dexamethasone on the incidence of postoperative nausea and vomiting (PONV) in patients undergoing modified radical mastectomy with neoadjuvant chemotherapy. ⋯ Dexamethasone prevents PONV effectively in patients undergoing modified radical mastectomy with neoadjuvant chemotherapy, and TIVA cannot decrease the incidence of PONV in the 24-hour postoperative period in those patients.
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Beijing Da Xue Xue Bao · Aug 2015
[Risk factors for the development of postoperative paralytic ileus after radical cystectomy: a report of 740 cases].
To identify the risk factors that would aid in the identification of patients at the greatest risk of developing postoperative paralytic ileus. ⋯ Increasing age, decreasing BMI, ileal conduiturinary diversion and pelvic lymph node dissection were significantly correlated with the presence of postoperative paralytic ileus in patients undergoing radical cystectomy.
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Beijing Da Xue Xue Bao · Aug 2015
[Effects of sevoflurane on brain neuroapoptosis and ability of long-term learning and memory in newborn rats].
To investigate the changes of neuroapoptosis in brain and learning ability after neonatal mice are exposed to inhaled sevoflurane. ⋯ Exposure to the concentration of 2% sevoflurane causes brain cell apoptosis of newborn rats. The memory ability to pessimal stimulation is decreased as the anesthesia mice were 5-week-old, such changes recede along with the growth of the rats. Exposure to the concentration of 2% sevoflurane does not affect the spatial reference memory of newborn rats during their growth.