Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences
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Beijing Da Xue Xue Bao · Dec 2006
[Protective effect of heme oxygenase-1 and its reaction product, carbon monoxide on acute liver injury induced by carbon tetrachloride in rats].
To investigate the protective role of heme oxygenase-1 and its reaction product, carbon monoxide against acute liver injury induced by carbon tetrachloride in rats. ⋯ The above results suggest that HO-1/CO system has a potent protective effect on acute liver injury induced by carbon tetrachloride in rats. Induction of HO-1 expression and low concentration of CO can inhibit the progress of hepatic damage, which might be due to the alleviation of lipid peroxidation and reduction of caspase-3 activity or inhibition of TNF-alpha level.
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Beijing Da Xue Xue Bao · Oct 2006
Randomized Controlled Trial[Effects of different methods of anesthesia and analgesia on early postoperative cognitive dysfunction after non-cardiac surgery in the elderly].
To determine if different methods of anesthesia and analgesia will influence the incidence of early postoperative cognitive dysfunction (POCD) after non-cardiac surgery in the elderly. ⋯ Early POCD occurred in 46.7% of the elderly patients undergoing abdominal surgery. However, there was no significant difference between the effects of two different methods of anesthesia and postoperative analgesia on the incidence of POCD. Short duration of education and operation of general surgery were risk factors of early POCD.
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Beijing Da Xue Xue Bao · Aug 2006
[Chloroquine increased radiosensitivity of radioresistant MDA-MB 231 cells and its molecular mechanism].
To study the genes associated with CQ (Chloroquine) increased radiosensitivity in radioresistant MDA-MB 231 cells. ⋯ CQ can increase radiosensitivity in radioresistant MDA-MB 231 breast cancer cells. It is not related to MLH1, ERCC1, PARP, RAD51, XRCC4 genes. TNP3 may play an important role in CQ increase radiosensitivity in radioresistant MDA-MB 231 breast cancer cells.
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Beijing Da Xue Xue Bao · Aug 2006
[Value of serum procalcitonin in diagnosing bacterial lower respiratory tract infections in people with exacerbation of Chronic Obstructive Pulmonary Disease].
To investigate the changes and clinical implications of serum procalcitonin in exacerbation of chronic obstructive pulmonary disease (COPD). ⋯ Serum procalcitonin measurements in patients of an exacerbation of chronic obstructive pulmonary disease play a role in the diagnosis of bacterial infection.
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Beijing Da Xue Xue Bao · Aug 2006
[Changes in hemodynamics and oxygen metabolism of different Child-grade patients during orthotopic liver transplantation without veno-venous bypass].
To investigate the changes in hemodynamics and oxygen metabolism of different Child-grade patients during orthotopic liver transplantation (OLT) without veno-venous bypass. ⋯ The hemodynamic state of high cardiac output with low peripheral resistance deteriorated when patients' Child-grade shifted from A to C. VO2 was less than normal value during OLT until the end point.