Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences
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Beijing Da Xue Xue Bao · Jun 2006
Review[Prospect of hypoxia imaging of nuclear medicine in tumors].
Tumor tissue hypoxia is taken as an important biologic character of malignant tumors, it could reduce the therapeutic efficacy of radiotherapy and chemotherapy. Presenting a noninvasive approach in detecting hypoxic state in tumors, hypoxia imaging of nuclear medicine can be used in the differential diagnosis, prognosis evaluation and guiding therapy of malignant tumors.
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Beijing Da Xue Xue Bao · Apr 2006
[Effect of lidocaine on the impairment of learning and memory function and central cholinergic system after transient global cerebral ischemia in mice].
To evaluate the effects of lidocaine on the impairments of learning and memorial function and central cholinergic system after transient global cerebral ischemia in mice of different apolipoprotein E genotypes. ⋯ Transient global cerebral ischemia caused significant brain damages in both strains of mice, which were represented by decline of learning and memorial function and damage of the central cholinergic system. Compared with the C57 mice, the ApoE mice had enhanced susceptibility to global cerebral ischemic injury as shown by more severe decline of the learning and memorial function. In the C57 mice, lidocaine significantly worsened the ischemic brain damage. In the ApoE mice, however, lidocaine significantly alleviated the ischemic cerebral results.
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Beijing Da Xue Xue Bao · Oct 2005
Randomized Controlled Trial[Target-controlled infusions of remifentanil and propofol in elderly patients].
To investigate the clinical reliability and feasibility of target-controlled infusion (TCI) with different plasma concentration remifentanil and propofol. ⋯ Remifentanil with plasma concentration of 4 and 7 microg/L combined with propofol could be safely used during clinical anesthesia of old patient, but monitoring must be strengthened during induction when plasma concentration of remifentanil was 7 microg/L. TCI propofol with Marsh parameters could be applied to Chinese elderly patients safely and efficiently.
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Beijing Da Xue Xue Bao · Oct 2005
[Application of sensitive sulphur electrode assay to measure and analyze cystathionine-gamma-lyase/hydrogen sulfide pathway of cardiovascular tissues, cells and plasma in rats].
To construct a method of measurement microamount hydrogen sulfide (H(2)S) using sensitive sulphur electrode. ⋯ The sensitive sulphur electrode assay was fit for the analysis of CSE/H(2)S pathway in cardiovascular research.
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Beijing Da Xue Xue Bao · Aug 2005
[Anti-endothelial cell antibodies(AECA) are associated with disease activity of propylthiouracil induced antineutrophil cytoplasmic antibody (ANCA) positive vasculitis].
To investigate the prevalence of anti-endothelial cell antibodies(AECA) and its possible role in the pathogenesis of propylthiouracil (PTU) induced ANCA positive vasculitis. ⋯ AECAs recognizing a variety of antigens could be found in sera from patients with PTU induced ANCA positive vasculitis and they had a much closer association with vasculitic disease activity compared with ANCA.