Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences
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Beijing Da Xue Xue Bao · Apr 2018
[Application of anoptomagnetic probe Gd-DO3A-EA-FITC in imaging and analyzing the brain interstitial space].
To investigate the application of the optical magnetic bimodal molecular probe Gd-DO3A-ethylthiouret-fluorescein isothiocyanate (Gd -DO3A-EA-FITC) in brain tissue imaging and brain interstitial space (ISS). ⋯ Gd-DO3A-EA-FITC shows the same imaging results as the traditional GD-DTPA, and it can be used in measuring brain ISS.
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Beijing Da Xue Xue Bao · Apr 2018
[Application of support vector machine in predicting in-hospital mortality risk of patients with acute kidney injury in ICU].
To construct an in-hospital mortality prediction model for patients with acute kidney injury (AKI) in intensive care unit (ICU) by using support vector machine (SVM), and compare it with the simplified acute physiology score II (SAPS-II) which is commonly used in the ICU. ⋯ Compared with the SAPS-II model, the SVM model has a better performance, especially when the mortality of a patient is with high uncertainty. The SVM model is more suitable for predicting the mortality of patients with AKI in ICU and early intervention in patients with AKI in ICU. The SVM model can effectively help ICU clinicians improve the quality of medical treatment, which has high clinical value.
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Beijing Da Xue Xue Bao · Apr 2018
[Role of aquaporin-4 in the change of interstitial fluid drainage in Alzheimer's disease].
To observe the characteristics of the interstitial fluid (ISF) drainage in the Alzheimer's disease (AD) rats through magnetic resonance imaging (MRI) tracer gadolinium-diethylene triamine pentacetic acid (Gd-DTPA)spread in the brain extracellular space (ECS) and to discuss the role of aquaporin-4 (Aqp4) in the AD. ⋯ The ISF drainage is slow after AD and the loss of Aqp4 in the AD makes the ISF drainage obviously slow down, Aqp4 plays an important role in AD to remove the metabolism of waste out of the brain.
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Beijing Da Xue Xue Bao · Dec 2017
Randomized Controlled Trial[Comparison of outcomes of two minimally invasive approaches for multi-vessel coronary revascularization].
To compare the safety and effectiveness of two minimally invasive approaches for multi-vessel coronary revascularization. ⋯ Staged-HCR is a feasible method for the treatment of multi-vessel revascularization involving right coronary artery. Minimally coronary revascularization with BITA is associated with superior long-term graft patency and it's recommended for patients who could not tolerate dual-antiplatelet therapy. This study shows that both minimally invasive surgical approaches are safe and effective for treatment of patients with multi-vessel coronary artery disease.
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Beijing Da Xue Xue Bao · Dec 2017
[Effect of different anesthetic methods on postoperative outcomes in elderly patients undergoing hip fracture surgery].
To investigate the effect of general or regional anesthesia on postoperative cardiopulmonary complications and inpatient mortality after hip fracture surgery in elderly patients. ⋯ General anesthesia may not affect the inpatient mortality after hip fracture surgery in elderly patients. Regional anesthesia is associated with a lower risk of pulmonary complications after surgical procedure compared with general anesthesia.