Mayo Clinic proceedings
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Mayo Clinic proceedings · Mar 2022
Comparisons of Insulin Spending and Price Between Canada and the United States.
Insulin prices have been a hot topic in the United States, where there is a lack of price regulation on drugs, and there have been reports of Americans crossing the border to purchase insulin in Canada at much lower prices. We conducted a cross-sectional time-series analysis comparing insulin spending using IQVIA (Durham, North Carolina, USA) data on aggregate insulin prescription volumes dispensed in the United States and Canada from January 2016 to April 2019 to quantify insulin spending and pricing differences between the countries. We obtained data on diabetes rates from the US Centers for Disease Control and Prevention and Statistics Canada. ⋯ Over the study period, the average cost per unit of insulin in the United States increased by 10.3% compared with only 0.01% in Canada. These findings demonstrate that the United States spent considerably more on insulin than Canada, and prices continue to increase. Implementing national legislation for drug pricing regulations using reference pricing could stabilize and potentially decrease insulin prices in the United States.
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Mayo Clinic proceedings · Mar 2022
The Lifestyle-Related Cardiovascular Risk Is Modified by Sleep Patterns.
To prospectively assess whether sleep patterns modified lifestyle-associated cardiovascular disease (CVD) risk. ⋯ Our results indicate that adherence to a healthy sleep pattern may attenuate the CVD risk associated with an unfavorable lifestyle.
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Mayo Clinic proceedings · Mar 2022
Risk of an Opioid-Related Emergency Department Visit or Hospitalization Among Older Breast, Colorectal, Lung, and Prostate Cancer Survivors.
To assess whether long-term cancer survivors (≥5 years after diagnosis) are at an increased risk of experiencing an opioid-related emergency department (ED) visit or hospitalization compared with persons without cancer. ⋯ Cancer survivors and noncancer controls had a similar risk of an ED visit or inpatient admission. Guidelines and policies should promote nonopioid pain management approaches especially to opioid non-naive older adults, a population at high risk for an opioid-related ED visit or hospitalization.
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Recognizing the contribution art has had in the Mayo Clinic environment since the original Mayo Clinic Building was finished in 1914, Mayo Clinic Proceedings features some of the numerous works of art displayed throughout the buildings and grounds on Mayo Clinic campuses as interpreted by the author.