Mayo Clinic proceedings
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Mayo Clinic proceedings · Mar 2021
Biography Historical ArticleJames Till and Ernest McCulloch: Hematopoietic Stem Cell Discoverers.
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Mayo Clinic proceedings · Mar 2021
Review Practice GuidelineMy Treatment Approach to Multiple System Atrophy.
Multiple system atrophy (MSA) is a neurodegenerative disorder primarily characterized by autonomic failure plus parkinsonism or cerebellar ataxia. The diagnosis may be challenging and is usually made at a tertiary care center. The long-term management issues are equally challenging and frequently require collaboration with the patient's local care providers. ⋯ Patients are often best served by management of their chronic and evolving complex problems with a team approach involving their primary care providers and subspecialists. Treatment guidelines typically list myriad therapeutic options without clarifying the most efficacious and simplest treatment strategies. Herein, we provide a guideline based on what has worked in our MSA clinic, a clinic designed to provide care throughout the disease course with subspecialty integration with the goal of empowering a partnership with the patient's home primary care providers.