Mayo Clinic proceedings
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Mayo Clinic proceedings · Jan 2009
Case ReportsCannabinoid hyperemesis relieved by compulsive bathing.
Cannabinoid hyperemesis is a clinical syndrome characterized by repeated vomiting and associated learned compulsive hot water bathing behavior due to long-term marijuana use. Research has identified type 1 cannabinoid receptors in the intestinal nerve plexus that have an inhibitory effect on gastrointestinal motility. ⋯ The thermoregulatory role of endocannabinoids may be responsible for the patient's need to take hot showers. We report 2 cases of cannabinoid hyperemesis that demonstrate this unusual adverse effect of marijuana use.
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Mayo Clinic proceedings · Dec 2008
Thunderclap headache and normal computed tomographic results: value of cerebrospinal fluid analysis.
To determine the sensitivity, specificity, and negative and positive predictive values of cerebrospinal fluid (CSF) xanthochromia for detection of ruptured cerebral aneurysms in patients with thunderclap headache (sudden and severe headache with maximal intensity at onset). ⋯ Although not perfect, visual inspection of CSF in patients with a history suggestive of subarachnoid hemorrhage remains a highly valuable and simple test to detect a recently ruptured aneurysm.
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Mayo Clinic proceedings · Dec 2008
Abnormal cardiac structure and function in the metabolic syndrome: a population-based study.
To measure the association between cardiac structure and function abnormalities and isolated metabolic syndrome (metabolic syndrome excluding established hypertension or diabetes mellitus). ⋯ Isolated metabolic syndrome, which is associated with increased LV mass index and LV diastolic dysfunction in women, identifies women with evidence of early ventricular dysfunction.
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Mayo Clinic proceedings · Nov 2008
Patterns of neuropathy and autonomic failure in patients with amyloidosis.
To define the clinical patterns of peripheral neuropathy and autonomic testing abnormalities in patients with amyloidosis. ⋯ Physicians should test for symptoms of generalized autonomic failure in patients who have peripheral neuropathy of unknown origin. Autonomic testing may give abnormal results in patients without overt symptoms of autonomic failure. Early recognition of autonomic failure may lead to earlier diagnosis of the underlying pathogenesis of amyloidosis, as well as earlier treatment for patients with this condition.