Mayo Clinic proceedings
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Mayo Clinic proceedings · Jul 2006
Multicenter Study Comparative StudyAdult intensive care unit use at the end of life: a population-based study.
To determine population-based rates of intensive care unit (ICU) use at the end of life in adults and describe demographic and clinical variation in end-of-life ICU use. ⋯ The rate of ICU use at the end of life Increases significantly with age and with the number of coexisting chronic illnesses.
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Mayo Clinic proceedings · Jul 2006
Randomized Controlled TrialPhase 2 study of pegylated liposomal doxorubicin, vincristine, decreased-frequency dexamethasone, and thalidomide in newly diagnosed and relapsed-refractory multiple myeloma.
To evaluate the efficacy and safety of adding thalidomide to the pegylated liposomal doxorubicin, vincristine, and decreased-frequency dexamethasone (DVd) regimen for multiple myeloma. ⋯ The addition of thalidomide to the DVd regimen significantly improves the response rate and quality of responses compared with the DVd regimen alone. This improvement is associated with longer progression-free and overall survival. The rate of observed quality responses is comparable to responses seen with high-dose therapy.
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Mayo Clinic proceedings · Jun 2006
Randomized Controlled TrialImprovement in fibromyalgia symptoms with acupuncture: results of a randomized controlled trial.
To test the hypothesis that acupuncture improves symptoms of fibromyalgia. ⋯ This study paradigm allows for controlled and blinded clinical trials of acupuncture. We found that acupuncture significantly improved symptoms of fibromyalgia. Symptomatic improvement was not restricted to pain relief and was most significant for fatigue and anxiety.