Mayo Clinic proceedings
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Mayo Clinic proceedings · Jul 2001
Symptom-triggered therapy for alcohol withdrawal syndrome in medical inpatients.
To assess the efficacy of symptom-triggered therapy vs usual care for alcohol withdrawal syndrome (AWS) in medical inpatients. ⋯ Symptom-triggered therapy is effective treatment for AWS in medical inpatients. In this retrospective study, it did not result in shorter duration of treatment but was associated with a decreased occurrence of delirium tremens, the most severe and life-threatening complication of AWS. This result was most apparent in patients with no history of delirium tremens.
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Mayo Clinic proceedings · Jun 2001
PSA doubling time as a predictor of clinical progression after biochemical failure following radical prostatectomy for prostate cancer.
To characterize the clinical progression of disease in men who have undergone prostatectomy for clinically localized prostate cancer and have postoperative biochemical failure (elevated prostate-specific antigen [PSA] level) and to identify predictors of clinical disease progression, including the possible effect of PSA doubling time (PSADT). ⋯ For patients who have undergone radical prostatectomy, a rising PSA level suggests evidence of residual or recurrent prostate cancer. Many men remain free of clinical disease for an extended time after biochemical failure following radical prostatectomy for clinically localized prostate cancer. The PSADT appears to be an important predictor of SP and also of any clinical progression (local or systemic). These data may be useful when counseling men regarding the timing of adjuvant therapies.
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Mayo Clinic proceedings · Jun 2001
Changes in testosterone, cortisol, and estradiol levels in men becoming fathers.
To quantify longitudinally steroid hormone (testosterone, cortisol, and estradiol) concentrations in men becoming fathers for the first time ("dads"). ⋯ In this population of Canadian volunteers attending prenatal classes, expectant fathers had lower testosterone and cortisol levels and a higher proportion of samples with detectable estradiol concentrations than control subjects. Individual patterns of testosterone variance relative to the birth and estradiol and cortisol concentrations immediately before the birth may be worthy of further investigation. The physiologic importance of these hormonal changes, if any, is not known. However, they are hormones known to influence maternal behavior.
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Mayo Clinic proceedings · Apr 2001
Randomized Controlled Trial Comparative Study Clinical TrialEffectiveness of resistive heating compared with passive warming in treating hypothermia associated with minor trauma: a randomized trial.
To determine the occurrence of hypothermia in patients with minor trauma, to test the hypotheses that resistive heating during transport is effective treatment for hypothermia and that this treatment reduces patients' thermal discomfort, pain, and fear, and to evaluate the accuracy of oral temperatures obtained at the scene of injury. ⋯ Oral temperatures are sufficiently accurate for field use. Hypothermia is common even in persons with minor trauma. Resistive heating during transport augments thermal comfort, increases core temperature, reduces pain and anxiety, and improves overall patient satisfaction.
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Mayo Clinic proceedings · Apr 2001
Comparative Study Clinical Trial Controlled Clinical TrialTreating fibromyalgia with a brief interdisciplinary program: initial outcomes and predictors of response.
To evaluate the efficacy of a brief, intense treatment program for fibromyalgia and to determine which patient characteristics are associated with a better treatment response. ⋯ A brief interdisciplinary program for treating fibromyalgia reduced some associated symptoms. Patients more severely affected by fibromyalgia may benefit most from this approach. Clinicians may apply these findings to develop beneficial and convenient treatment programs for patients with fibromyalgia.