Journal of comparative effectiveness research
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Cluster randomized trials are trials that randomize clusters of people, rather than individuals. They are becoming increasingly common. ⋯ This article will highlight and illustrate these developments. It will also discuss issues with regards to the reporting of cluster randomized trials.
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Evaluation of: Mol F, van Mello NM, Strandell A et al. Salpingotomy versus salpingectomy in women with tubal pregnancy (ESEP study): an open-label, multicentre, randomised controlled trial. Lancet 383(9927), 1483-1439 (2014). ⋯ To date, there is a wealth of data establishing laparoscopic treatment as the 'gold standard'; however, paradoxically, the evidence behind choosing the two main treatment methods of salpingotomy and salpingectomy, especially with regards to future fertility potential, remain unclear. This article is a summary of a randomized controlled trial of salpingotomy versus salpingectomy in patients with an apparent contralateral healthy tube and the impact on future fertility. It attempts to answer the clinical question whether preservation of tube by salpingotomy increases the futures chances of natural conception as opposed to salpingectomy.