Zhonghua bing li xue za zhi Chinese journal of pathology
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Zhonghua Bing Li Xue Za Zhi · Apr 2015
[Detection of KRAS,NRAS and BRAF gene mutations in colorectal carcinoma].
To investigate mutations frequencies of KRAS,NRAS and BRAF genes in colorectal carcinoma. ⋯ Mutations at exon 2 of KRAS gene have the highest frequency in colorectal carcinoma. Expanding the detection sites of KRAS gene combined with NRAS and BRAF genes may help to identify patients who will most likely benefit from targeted therapies.