International journal of clinical and experimental medicine
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Hepatic parenchymal bleeding (HPB) is a major problem following both trauma and elective hepatic procedures. The present study investigated the effect of the Ankaferd Blood Stopper® (ABS) on HPB. ⋯ Although the ABS does not stop HPB completely, it ensures a statistically significant reduction in HPB.
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There has been much effort to define the molecular basis by which pathophysiological stimuli initiate and/or propagate the inflammatory response. Recent research endeavors on stress response from a cellular organelle called the endoplasmic reticulum (ER) shed new light on the understating of the molecular basis of the inflammatory response and its interaction with other intracellular stress signaling pathways. ⋯ The integration of ER stress, oxidative stress, and the inflammatory response is critical to the pathogenesis of a variety of diseases. In this brief review, we discuss some representative evidence for the integration of ER stress, oxidative stress, and inflammation in health and disease.