Zhonghua wai ke za zhi [Chinese journal of surgery]
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Zhonghua Wai Ke Za Zhi · Feb 1996
[The correlation between gastric intramucosal pH and oxygen delivery in patients with septic shock].
We studied the correlation of intramucosal pH (pHi), oxygen delivery (DO2) and oxygen consumption (VO2) in 21 patients with septic shock, and found that pHi decreased dramatically (P < 0.05) in nonsurvivors while it had no significant change in survivors. In survivors, there was a positive correlation between pHi and DO2 (r = 0.71, P < 0.001), pHi and VO2 (r = 0.63, P < 0.001) when DO2 was below the critical level of 641 ml/min/m2. ⋯ The correlation between pHi and DO2 proves the oxygen supply dependency of VO2. The hypoxia in tissue level is the main factor which results in a high mortality of septic shock patients. pHi is a reliable and useful parameter not only for prognosis, but also for titrating the therapy in septic shock if pHi is monitored serially together with DO2.