Ultrasound in medicine & biology
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Ultrasound Med Biol · Oct 2008
Comparative Study Controlled Clinical TrialDo bubble characteristics affect recanalization in stroke patients treated with microbubble-enhanced sonothrombolysis?
Administration of microbubbles (MB) may augment the effect of ultrasound-enhanced systemic thrombolysis in acute stroke. Bubble structural characteristics may influence the effect of MB on sonothrombolysis. We aimed to compare the effects of galactose-based air-filled MB (Levovist) and sulphur hexafluoride-filled MB (Sonovue) on recanalization and clinical outcome. ⋯ Forty-four percent of patients in the LV group and 48.5% in the SV group achieved functional independence (mRS