JAAPA : official journal of the American Academy of Physician Assistants
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Sofosbuvir, a nucleotide polymerase inhibitor, was approved in 2013 for treating hepatitis C infection in adults. This article reviews the use of sofosbuvir in combination with ribavirin with or without pegylated interferon.
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The largest-ever outbreak and first epidemic of Ebola virus disease is affecting several West African countries. Early symptoms of Ebola can mimic those of other tropical diseases. In a world of rapid global travel, physician assistants need to be capable of identifying patients at greatest risk for developing Ebola. Clinicians also should be familiar with associated symptoms, diagnosis, and treatment considerations.