Nan fang yi ke da xue xue bao = Journal of Southern Medical University
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Nan Fang Yi Ke Da Xue Xue Bao · Oct 2008
[Effect of age on ED50 of rocuronium for intratracheal intubation in female patients].
To determine the half-effective dose (IED50) of rocuronium for intratracheal intubation in female patients of different ages by sequential experiments and evaluate the effect of age on IED50 of rocuronium. ⋯ The IED50 of rocuronium is significantly lower in elderly female patients than in young female patients, suggesting the necessity of reducing the dose of rocuronium accordingly in anesthesia induction in elderly female patients.
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Nan Fang Yi Ke Da Xue Xue Bao · Oct 2008
[Effects of intrathecal ouabain and tizanidine injection for treatment of neuropathic pain in rats].
To investigate the effects of intrathecal ouabain and tizanidine injection for treatment of neuropathic pain in rats. ⋯ Intathecal injection of ouabain or tizanidine produces dose-dependent analgesic effects against neuropathic pain, and their synergistic effect after combined injection probably involves the cholinergic transmission and alpha2 receptor.