Nan fang yi ke da xue xue bao = Journal of Southern Medical University
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Nan Fang Yi Ke Da Xue Xue Bao · Jun 2012
[A retrospective analysis of fluid resuscitation in 94 patients with extensive burns].
To analyze the clinical data of adult patients with total burn surface area (TBSA) greater than 50% in Guangzhou and explore the optimal fluid resuscitation protocols for these patients. ⋯ For patients with extensive burns, an individualized fluid resuscitation regimen, an adequately high colloid/crystal rehydration ratio, and a greater total infusion volume according to the local climate of Guangzhou can be beneficial to reduce the incidence of visceral complications and the mortality rate.
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Nan Fang Yi Ke Da Xue Xue Bao · Jun 2012
[Blocking p38 signal pathway lowers MMP-9 expression and reduces brain edema in rats with traumatic brain injury].
To explore the role of p38 signal pathway in regulating matrix metalloproteinase-9 (MMP-9) expression and brain edema formation in a rat model of traumatic brain injury (TBI). ⋯ Blocking p38 signal pathway can attenuate MMP-9 upregulation and brain edema after TBI, suggesting the important role of p38 in regulating MMP-9 expression to affect traumatic brain edema.
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Nan Fang Yi Ke Da Xue Xue Bao · Jun 2012
[Ulinastatin combined with thymosin α1 for treatment of severe sepsis: a histopathological observation in rats].
To evaluate the therapeutic effect of ulinastatin combined with thymosin α1 in the treatment of severe sepsis in rats. ⋯ Combined treatment with ulinastatin and thymosin α1 can significantly improve the prognosis and ameliorate organ damage and spleen cell apoptosis in rats with sever sepsis.