Nan fang yi ke da xue xue bao = Journal of Southern Medical University
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Nan Fang Yi Ke Da Xue Xue Bao · Aug 2015
[Effect of neonatal perioperative anesthetic exposure in cardiac surgery on neuro- developmental outcomes in preschool children].
To evaluate the effect of neonatal perioperative anesthetic exposure in complex cardiac surgery on neurodevelopmental outcomes in preschool children. ⋯ We found a significant association of days on benzodiazepines, cumulative dose of benzodiazepines, and days on chloral hydrate in neonatal cardiac surgery with neurodevelopmental outcomes at the preschool age, suggesting the need of minimizing anesthetic exposure during a neonatal cardiac surgery to improve the children's neurodevelopmental outcomes.
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Nan Fang Yi Ke Da Xue Xue Bao · Aug 2015
[Mechanism of continuous venovenous hemofiltration combined with ulinastatin for the treatment of septic shock].
To investigate the molecular mechanisms of continuous venovenous hemofiltration (CVVH) combined with ulinastatin (ULI) (CVVH-ULI) for the treatment of septic shock. ⋯ CVVH combined with ulinastatin decreases endothelial hyperpermeability induced by septic shock through inhibiting p38 MAPK pathways.
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Nan Fang Yi Ke Da Xue Xue Bao · Aug 2015
[Minocycline reduces hyperpolarization-activated current in rat substantia gelatinosa neurons].
To investigate the effect of minocycline on hyperpolarization-activated current (Ih) in the substantia gelatinosa (SG) neurons in rat spinal dorsal horn. ⋯ Minocycline suppresses the excitability of SG neurons through inhibiting the amplitude and current density of Ih and thereby contributes to pain modulation.
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Nan Fang Yi Ke Da Xue Xue Bao · Aug 2015
[Structural changes in the gray matter in patients with trigeminal neuralgia: a voxel-based morphometric study].
To investigate the changes in whole brain gray matter volume in patients with trigeminal neuralgia using voxel-based morphometry (VBM). ⋯ Patients with trigeminal neuralgia had abnormal gray matter volume in some brain regions associated with perception and processing of pain sensation. These changes may provide clues for further exploration of the neuropathogenic basis of trigeminal neuralgia.