Kyobu geka. The Japanese journal of thoracic surgery
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A 33-year-old male was involved in a single motor vehicle accident and was referred to our hospital 135 minutes after injury. He had a sign of cardiac tamponade and immediately pericardial window was performed at the emergency department, but hypotension went worse. ⋯ Cardiac rupture due to blunt trauma is highly lethal, and prompt diagnosis is necessary for a favorable outcome. A high index of suspicion, avoidance of unnecessary diagnostic studies, and immediate surgical intervention are critical for successful management.
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Clinical Trial
[Effectiveness of low dose continuous infusion of alpha-hANP from the start of cardiopulmonary bypass].
In this study, we used alpha-human atrial natriuretic peptide (hANP) from staring on cardiopulmonary bypass and evaluated for the hemodynamics, ANP, renin activity, aldosterone, urine volume, glomerular filtration rate (GFR) and so on. The hANP decreased renin activity, aldosterone, systemic vascular resistance and increased urine volume, GFR and use of furosemide and KCL were decreased. We concluded that hANP was effective for hemodynamics, renal function and hormonal release on intra and post-operation in cardiac surgery, and low dose continuous infusion of alpha-hANP from staring on cardiopulmonary bypass will be expected as a newly application.