Japanese heart journal
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Japanese heart journal · Jul 1982
Reliability of telephone transmission facilities for computerized electrocardiogram analysis in Japan.
The reliability of telephone electrocardiogram (ECG) transmission facilities was assessed in order to carry out the computerized ECG analysis using the IBM-Bonner program. Simulated ECGs were transmitted repeatedly over telephones from an internal laboratory and from an external hospital which was 1,000 Km distant. The simulated ECG was transmitted in a highly reproducible state and with no appreciable distortion. The telephone ECG transmission facilities using the public telephone network in Japan proved to reliable for computerized ECG analysis.
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Japanese heart journal · Jul 1982
A clinical study on the role of the renin-angiotensin-aldosterone system and catecholamines in chronic congestive heart failure.
In order to evaluate the roles of the renin-angiotensin-aldosterone system and of catecholamines in 117 normotensive patients with chronic congestive heart failure (CHF), a study was made of the relationships between plasma concentrations, hepatic extraction of these humoral factors and hemodynamic parameters. In 6 patients with moderate to severe CHF, the acute effect of oral; administration of angiotensin I converting enzyme inhibitor, SQ 14225 (captopril), on mean arterial pressure (MAP), peripheral venous pressure (VP) and these humoral factors was investigated. In patients with CHF of Class III-IV (according to NYHA classification), the urinary norepinephrine (U-NE) excretion increased. ⋯ These findings suggest that the sympathetic nervous system contributes to the elevation of SVR and PWP even before frank heart failure develops. The rise of P-NE seems to be due to increased norepinephrine release from sympathetic nerve beds, whereas a decrease in hepatic extraction and renal clearance probably has only a minor effect. The renin-angiotensin system also seems to contribute to elevation of SVR, to maintain effective arterial pressure by enhanced sympathetic activity, and the renin-angiotensin system seems to be a main determinant of PA in CHF.