Chang Gung medical journal
-
This study examined whether different ondansetron dosing schedules plus dexamethasone influenced antiemetic efficacy during multiple cycles of cisplatin-based chemotherapy (CT). Antiemetic activities between previous CT and subsequent cycles were compared. ⋯ No difference in antiemetic efficacy was shown when a triple 8 mg dose of ondansetron was given at 4-hourly intervals or at 24-hourly intervals. However, the latter improved nausea on day 2. A single 8 mg dose of ondansetron can maintain antiemetic efficacy in the majority of complete responders in arm A and arm B.
-
Sleep-disordered breathing (SDB) is a prevalent disorder that has a huge impact on the public. It has been proposed that Chinese populations have a higher incidence of SDB than Caucasians due to a narrow cranial base and flat mid-face structure. Few studies have investigated the prevalence of SDB in Taiwan. This study prospectively assesses the complaints of SDB and related conditions via telephone interviews with individual older than fifteen in Taiwan to calculate a possible prevalence. ⋯ This study determined that 51.9% (95% CI 51.13%-52.67%) of Taiwanese snore and 2.6% (95% CI 2.1%-3.1%) have witnessed apnea. Those who snore or have witnessed apnea have a higher incidence of comorbidity with major medical diseases compared to those who do not snore or do not have witnessed apnea.