Tidsskrift for den Norske lægeforening : tidsskrift for praktisk medicin, ny række
-
Diet is one of many factors that could alter the pharmacokinetics of drugs. Several fruits and berries have recently been shown to contain agents that affect drug-metabolizing enzymes. Grapefruit is the most well-known example, but also Sevillian orange, pomelo and star fruit contain agents that inhibit cytochrome P450 3A4 (CYP3A4), which is the most important enzyme in drug metabolism. The present article reviews published information on potential interactions between drugs and fruits/berries, with main focus on inhibition and induction of metabolizing enzymes.
-
Tidsskr. Nor. Laegeforen. · Dec 2007
Biography Historical Article[Vladimir Bechterew--the professor stopped by Stalin].
-
Tidsskr. Nor. Laegeforen. · Dec 2007
Biography Historical Article[La donna é mobile--the hysteria diagnosis in Norway in the 19th century].
The last half of the 19 th century has been described as "the golden age of hysteria". Hysteria was a frequently used diagnosis in this period and received increasing attention from a number of prominent medical researchers, such as Jean-Martin Charcot and Sigmund Freud in Europe and for example Edvard Bull, Paul Winge and Ragnar Vogt in Norway. ⋯ The symptoms are described as comprehensive, and several different etiological models can be traced. Even though hysteria is not exclusively associated with the female body and psyche, it is constructed at the interface of scientific opinion and notions of femininity.