The Canadian journal of hospital pharmacy
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Pain associated with infiltrating the skin with lidocaine can be reduced by buffering the solution with sodium bicarbonate. ⋯ Extemporaneously prepared buffered lidocaine (1% and 2%) packaged in polypropylene syringes remained stable for up to 28 days when properly refrigerated with protection from light. A 7-day expiry date was established for buffered lidocaine solutions containing epinephrine, packaged in polypropylene syringes, and stored with refrigeration and protection from light.