Vnitr̆ní lékar̆ství
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Vnitr̆ní lékar̆ství · Dec 2001
Review[Extravascular lung water in acute respiratory distress syndrome: pathophysiology, monitoring and therapeutic possibilities].
Excessive amount of extravascular lung water (EVLW) resulting from increased permeability of alveolo-capillary membrane is a pathophysiological hallmark of acute respiratory distress syndrome (ARDS). Increased EVLW produces hypoxemia by interference with gas exchange. ⋯ The presented paper briefly reviews the mechanisms involved in lung edema formation and describes current options to measure EVLW. In addition, it discusses clinical implications of EVLW measurement in intensive care setting with particular focus on transpulmonary indicator dilution technique.