Vnitr̆ní lékar̆ství
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Vnitr̆ní lékar̆ství · Oct 2003
Comparative Study[Comparison of various methods of correction of QT intervals during exercise in familial long QT interval syndrome].
Pathologic prolongation of QT interval is related to increased risk of arrhythmias. Changes of this parameter are influenced by many conditions, the most important is heart rate. Several formulas have been proposed for mathematical description of QT interval/heart rate relationship. The aim of this study was comparison of different QT interval correction formulas in families with congenital long QT syndrome (LQTS). ⋯ Because of simplicity the Bazett formula remains the most common method of QT interval correction. Moreover, in our study this formula appeared to be the most sensitive for clinical diagnosis of LQTS.