International journal of spine surgery
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The purpose of this study was to record the frequency of lumbar intervertebral disc vacuum phenomenon on routine lumbar plain films taken prior to transforaminal endoscopic decompression surgery for sciatica-type leg and back pain and to correlate it with visualized intradiscal pathology and clinical outcomes. ⋯ A vacuum phenomenon seen on lumbar x-rays is highly specific for a source of one component that is actually a multiple source of nonspecific common back pain. A vacuum disc being found during "inside-out" transforaminal discectomy actually encompasses the disc, annulus, and foraminal stenosis as a multifactorial source of nonspecific common back pain. Further studies of better prognosticators of failed endoscopic transforaminal discectomy are required and are underway by the coauthors.
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Insufficient data exist on bone graft substitute materials efficacy; two thirds lack any clinical data.1,2 This prospective animal study identified efficacy differences among commercially available materials of several classes. ⋯ When selecting DBMs, clinicians must be cognizant of variability in DBM efficacy by product and lot. While theoretically osteoinductive, cellular allograft and activated ceramics yielded poor in vivo efficacy. Whole allograft and ceramics may provide osteoconductive scaffolding for mixed-material grafting; however, surgeons should be cautious in using them alone. Direct clinical data are needed to establish efficacy for any bone graft substitute.