The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists
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Opioid analgesics are commonly used medications for the treatment of acute and chronic pain syndromes associated with multiple disease states. However, their use is often limited by adverse effects. Opioid-induced pruritus (OIP) is one of the most common adverse effects, affecting patients on oral and neuraxial opioids. ⋯ The occurrence of pruritus varies with the type of opioid, dose, and method of administration. Pharmacists can make interventions that will optimize control of, or reduce the incidence of, OIP. An understanding of the receptors, mechanisms, incidence, and pharmacological therapies available to manage OIP is required knowledge for practitioners caring for patients who use opioids.