The journal of allergy and clinical immunology. In practice
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J Allergy Clin Immunol Pract · Mar 2015
Review Meta AnalysisNetwork meta-analysis shows commercialized subcutaneous and sublingual grass products have comparable efficacy.
Subcutaneous immunotherapy (SCIT) and sublingual immunotherapy (SLIT) have been shown to effectively treat grass pollen allergies, although direct comparisons are sparse. ⋯ The comparisons for grass pollen immunotherapy products commercialized in at least 1 country indicate comparable reductions in allergic rhinoconjunctivitis symptoms and supplemental medication use for SLIT tablets and SCIT in the first pollen season.
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Little is known about the adherence rate to allergen immunotherapy (AIT) labeling guidelines. ⋯ Fewer than 25% of the nonuniversity prescribers adhered to AIT practice parameters 5 years after publication. Recording 2 PIs, the v/v concentration, or the color coding increased the likelihood of having a complete label. Complete label contents were associated with clear instructions about AIT dosing and reaction treatment and/or dose adjustments.