Prescrire international
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Prescrire international · Sep 2013
Secondary cardiovascular prevention: omega-3 fatty acids ineffective.
A meta-analysis of comparative clinical trials including about 20,000 patients with a history of cardiovascular disease showed that omega-3 fatty acid supplementation did not reduce the risk of a subsequent cardiovascular event.
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Prescrire international · Sep 2013
Intranasal live attenuated seasonal influenza vaccine: does not challenge current practice.
Influenza vaccination of children is only justified when there is a risk of serious influenza complications. In 2012, a live attenuated vaccine for intranasal administration was authorised in the European Union for influenza prevention in individuals aged from 2 to less than 18 years. This type of vaccine has been available in the United States since 2003. ⋯ In practice, there is no firm evidence that this live attenuated influenza vaccine has any clinical advantages over injected vaccines, including in children at risk of influenza complications. In addition, this vaccine is unsuitable for the very children who are most in need of protection against influenza. It is better to stick with injected influenza vaccines.