Yonsei medical journal
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Yonsei medical journal · Apr 2007
Randomized Controlled TrialIntra-synovial ropivacaine and morphine for pain relief after total knee arthroplasty: a prospective, randomized, double blind study.
Several analgesic techniques are available for pain management after a major operation. ⋯ Therefore, we found that ropivacaine, alone or with morphine, injected into the synovial tissue, along with an epidural PCA has no additional benefits in pain control after a total knee arthroplasty.
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Yonsei medical journal · Apr 2007
Case ReportsBupivacaine induced cardiac toxicity mimicking an acute non-ST segment elevation myocardial infarction.
Bupivacaine is widely used as a local anesthetic. Central nervous system (CNS) and cardiovascular toxicity are well known side effects. However, there has been no report of bupivacaine-induced myocardial injury. ⋯ We diagnosed the patient as having acute non-ST segment elevation myocardial infarction but her impaired cardiac function improved gradually. On the seventh day from admission, there was a complete spontaneous recovery of cardiac function, and coronary angiography revealed a normal coronary artery. Therefore, we firmly believe that bupivacaine directly injures the cardiac cell.
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There has been growing interest in the use of grafts in pelvic reconstructive surgery. This article will address available graft materials and assess their clinical efficacy and safety. We conducted a Pubmed MEDLINE literature search for full-length English text studies with follow-up periods of at least one year. ⋯ There is insufficient evidence in favor of biological grafts. In conclusion, based on current knowledge, routine application of grafts in pelvic reconstruction is not recommended. It is preferred that graft utilization be individualized, with close monitoring for complications.