Yonsei medical journal
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Yonsei medical journal · Jul 2016
Observational StudyThe Effect of Pulsatility Index on Infarct Volume in Acute Lacunar Stroke.
Lacunar stroke, in the context of small vessel disease, is a type of cerebral infarction caused by occlusion of a penetrating artery. Pulsatility index (PI) is an easily measurable parameter in Transcranial Doppler ultrasound (TCD) study. PI reflects distal cerebral vascular resistance and has been interpreted as a surrogate marker of small vessel disease. We hypothesized that an increased PI, a marker of small vessel disease, might be associated with a larger infarct volume in acute lacunar stroke. ⋯ We demonstrated that PI was an independent determinant of infarct volume in acute lacunar stroke. The PI value measured in acute stroke may be a surrogate marker of the extent of ischemic injury.
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Yonsei medical journal · Jul 2016
Erratum to "Snakebite in Korea: A Guideline to Primary Surgical Management" by Rha JH, et al. (Yonsei Med J 2015;56:1443-8.).
This corrects the article on p. 1443 in vol. 56, PMID: 26256993.
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Yonsei medical journal · Jul 2016
Preclinical Study of Cell Therapy for Osteonecrosis of the Femoral Head with Allogenic Peripheral Blood-Derived Mesenchymal Stem Cells.
To explore the value of transplanting peripheral blood-derived mesenchymal stem cells from allogenic rabbits (rPBMSCs) to treat osteonecrosis of the femoral head (ONFH). ⋯ We confirmed that local transplantation of rPBMSCs benefits ONFH treatment and that the beneficial effects are related to the up-regulation of BMP-2 expression and the down-regulation of PPAR-γ expression.
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Yonsei medical journal · Jul 2016
Meta AnalysisAldehyde Dehydrogenase 2 (ALDH2) Polymorphism and the Risk of Alcoholic Liver Cirrhosis among East Asians: A Meta-Analysis.
The aldehyde dehydrogenase 2 (ALDH2) gene has been implicated in the development of alcoholic liver cirrhosis (ALC) in East Asians. However, the results are inconsistent. In this study, a meta-analysis was performed to assess the associations between the ALDH2 polymorphism and the risk of ALC. ⋯ The pooled evidence suggests that ALDH2 polymorphism may be an important protective factor for ALC in East Asians.
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Yonsei medical journal · Jul 2016
Re-Irradiation for Recurrent Gliomas: Treatment Outcomes and Prognostic Factors.
The aim of this study was to evaluate the efficacy of re-irradiation in patients with recurrent gliomas and to identify subgroups for whom re-irradiation for recurrent gliomas is most beneficial. ⋯ Re-irradiation in conjunction with surgery could be a salvage treatment for selected recurrent glioma patients with good performance status and recurrence over a long time.