Yonsei medical journal
-
Yonsei medical journal · Jan 2019
ReviewAntineutrophil Cytoplasmic Antibody-Associated Vasculitis in Korea: A Narrative Review.
Antineutrophil cytoplasmic antibody-associated vasculitis (AAV) is a group of systemic necrotising vasculitides, which often involve small vessels, and which lead to few or no immune deposits in affected organs. According to clinical manifestations and pathological features, AAV is classified into three variants: microscopic polyangiitis, granulomatosis with polyangiitis (GPA), and eosinophilic GPA. The American College of Rheumatology 1990 criteria contributed to the classification of AAV, although currently the algorithm suggested by the European Medicines Agency in 2007 and the Chapel Hill Consensus Conference Nomenclature of Vasculitides proposed in 2012 have encouraged physicians to classify AAV patients properly. ⋯ Furthermore, initial vasculitis activity, prognostic factor score, age and specific organ-involvement have been found to be associated with either all-cause mortality or poor disease course. The rate of serious infection is 28.6%, and 1 year-, 5 year- and 10 year-cumulative hospitalised infection free survival rates range from 85.1% to 72.7%. The overall standardised incidence ratio of cancer in AAV patients was deemed 1.43 compared to the general Korean population.
-
Yonsei medical journal · Jan 2019
Up-Regulation of MiR-1915 Inhibits Proliferation, Invasion, and Migration of Helicobacter pylori-Infected Gastric Cancer Cells via Targeting RAGE.
Helicobacter pylori (HP)-infected gastric cancer (GC) is known to be a fatal malignant tumor, but the molecular mechanisms underlying its proliferation, invasion, and migration remain far from being completely understood. Our aim in this study was to explore miR-1915 expression and its molecular mechanisms in regulating proliferation, invasion, and migration of HP-infected GC cells. ⋯ MiR-1915 exerted tumor-suppressive effects on cellular proliferation, invasion, and migration of HP-infected GC cells via targeting RAGE, which provided an innovative target candidate for treatment of HP-infected GC.
-
Yonsei medical journal · Jan 2019
Retraction Of PublicationRetraction: Paper "Differential Effect of Vitamin K and Vitamin D Supplementation on Bone Mass in Young Rats Fed Normal or Low Calcium Diet" by Iwamoto J, et al. [Yonsei Med J 2004;45(2):314-324].
This corrects the article on p. 314 in vol. 45, PMID: 15119005.
-
Yonsei medical journal · Jan 2019
Retraction Of PublicationRetraction: Paper "Comparison of Effect of Treatment with Etidronate and Alendronate on Lumbar Bone Mineral Density in Elderly Women with Osteoporosis" by Iwamoto J, et al. [Yonsei Med J 2005;46(6):750-758].
This corrects the article on p. 750 in vol. 46, PMID: 16385649.
-
Yonsei medical journal · Jan 2019
Matrine Suppresses Pancreatic Fibrosis by Regulating TGF-β/Smad Signaling in Rats.
This study aimed to elucidate the molecular mechanisms of the anti-pancreatic fibrosis effects of matrine in rats. ⋯ Matrine suppressed pancreatic fibrosis by regulating TGF-β/Smad signaling in rats.