Multiple sclerosis and related disorders
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Mult Scler Relat Disord · Jan 2014
NMO spectrum disorders comprise the major portion of CNS inflammatory diseases in Thai patients: A cross sectional study.
Neuromyelitis optica (NMO) is more prevalent than multiple sclerosis (MS) in the Asian population. AQP4-IgG as a specific biomarker for NMO has not been systematically validated in Thai patients. ⋯ NMOSD is more common than MS in Thai patients. Moreover, AQP4-IgG is highly specific for NMOSD. Spinal MRI can effectively distinguish NMOSD from MS patients. AQP4-IgG seropositivity is highly correlated with females and the presence of optic neuritis.