Bulletin du cancer
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Randomized Controlled Trial Multicenter Study Comparative Study
PCA analgesia for children with chemotherapy-related mucositis: a double-blind randomized comparison of morphine and pethidine.
This study aimed to compare pethidine and morphine on efficacy and toxicity in children with severe mucositis following chemotherapies. ⋯ PCA with pethidine appears not inferior to morphine, with less constipation requiring specific treatment, but a larger study is warranted to confirm this.