Archives of otolaryngology--head & neck surgery
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Arch. Otolaryngol. Head Neck Surg. · Oct 2009
Randomized Controlled TrialThe hemostatic and hemodynamic effects of epinephrine during endoscopic sinus surgery: a randomized clinical trial.
To assess the hemodynamic and hemostatic effects of 2 different concentrations of epinephrine in local anesthetic used during functional endoscopic sinus surgery (FESS). Injection of local anesthetic containing epinephrine during endoscopic sinus surgery, while providing hemostasis, has been associated with cardiac adverse effects such as tachycardia, hypertension, as well as arrhythmias. ⋯ Submucosal injection of lidocaine, 2%, with 1:200 000 epinephrine during FESS does not lead to hemodynamic fluctuations or increased intraoperative bleeding compared with lidocaine, 2%, with 1:100 000 epinephrine.