Archives of general psychiatry
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Arch. Gen. Psychiatry · Mar 2012
A dynamic view of depressive symptoms and neurocognitive change among patients with coronary artery disease.
Older patients with coronary artery disease often experience depressive symptoms and are vulnerable to developing cognitive impairment. Whether depressive symptoms increase their risk of cognitive decline is unknown. ⋯ Depressive symptoms persist in some patients with coronary artery disease, placing them at a greater risk for cognitive decline. Whether this decline is additionally modified by the presence of APOE ε4 requires further investigation.