Polski przeglad chirurgiczny
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Comparative Study
The relative frequency of the Helicobacter pylori infection in proximal gastric cancers.
Gastric cancer with the annual mortality of 700 000 is the second cause of death in the world. Iran with the annual incidence of 37 in 100 000 is among areas with high risk of gastric cancer. In Iran, Khuzestan Province with the annual incidence of 10 -15 in 100 000 is among areas with moderate risk. The role of Helicobacter pylori infection in distal gastric cancer as one of the most important risk factors of gastric ulcer has been proved but its role in proximal gastric cancer is controversial. In recent decades, the incidence of proximal cancers has increased. The aim of the study was to survey the relative frequency of Helicobacter pylori infection in the people with proximal cancer and to compare it with this infection frequency in the distal cancer. ⋯ A weak significant difference existed between the frequency of Helicobacter pylori infection in patients with the proximal gastric cancer and the frequency of these infections in the patients with the distal cancer. So, eradicating Helicobacter pylori infection can be effective in preventing the distal gastric cancers in addition to preventing the proximal gastric cancers.